Kufutisa kwave kuita chirwere chepasi rose, kubata mamirioni avanhu pasi rese. Pasinei nezviyero zvehuremu hwekurema kwemhinduro dziripo, vanhu vazhinji vanonetseka kuzadzisa uye kuchengetedza huremu hwavo hwaunoda. Nekudaro, kufambira mberi kwazvino musainzi yezvesayenzi zvakavezwa nenzira yekuvimbisa kurapa, senge semaglutudide majekiseni. Aya majekiseni akambobuda semutambo-wekuchinja-chinjana muhondo yekufutirwa, kupa mhinduro inoshanda uye yakakodzera kwazvo yekudzora kwenguva refu.
Munyaya ino, isu tichakurudzira mune zvakanakira Semaglutide majekiseni , ongorora kuti vanoshanda sei, uye kurukura kwavo kugona kushandura hupenyu hwevanonetseka nekufutisa. Kunyangwe iwe uri nyanzvi yehutano kutsvaga nzira dzekunyepedzera dzevarwere vako kana munhu anotarisa kuti utange kuremerwa nehuremu hwesimba rekusimbisa kwemigariro mukuzadza huremu hwekuremerwa uye nekuvandudza hutano hwese.
Kunzwisisa Semaglutudide uye Mechanism yayo yekuita
Semaglutide inalox onelogue yemunhu glucagagon-1 (GLP-1) hormone, inotamba basa rakakosha mukudzora nzara uye mwero wetsiva. Pakutanga yakagadziridzwa sokurapa kwerudzi rwechipiri chirwere cheshuga, asi huremu hwayo hunoshamisa hwakakurumidza kubata vaongorori uye nyanzvi dzehutano.
Kana ikapinda mumuviri, semaglutudi inotarisa chiito cheGLP-1, kumutsa kusunungurwa kwe insulin uye inhibiting seclongsion. Ichi chiitiko chechiitiko chinobatsira kudzikisa ropa shuga yeropa uye kusimudzira uremu kurasikirwa nekudzora nzara uye kuwedzera manzwiro ekuzara. Semaglutide zvakare inodzora gastric kusundira, kuwedzera kupa kune kwayo kwekudya kwayo-kudzvinyirira mhedzisiro.
Miedzo yekiriniki yakaratidza kushanda kweiyo semaglutudide mukusimudzira kukosha kwehuremu. Mune chidzidzo chakaburitswa muNew England Journal yeMishonga, vatori vechikamu vakagamuchira svondo sevartide majekiseni vakawana uremu uremu hwemakore makumi matatu nemasere, vachienzaniswa nemavhiki makumi matanhatu neshanu. Mhedzisiro idzi dzakashatisa munharaunda yekurapa uye pakati pevanhu vanonetseka nekufutisa, sezvo semaglutide inopa mhinduro inobudirira uye yakakodzera kwazvo yekuita kureba.
Zvakanakira Semaglutudide majekiseni ekurasikirwa uremu
Chimwe chezvakanyanya kubatsira Semaglutide majekiseni jekiseni yavo yekukoshesa zvakanyanya uye yakasimba kurema uremu. Kusiyana nedzimwe humwe huremu kurasikirwa kurapwa kunopa chete mhinduro pfupi, Semaglutudide yakaratidzirwa kubatsira kubatsira vanhu kuti varambe vakasununguka kurema nekuda kwenguva yakareba.
Izvi zvinonyanya kukosha nekuti uremu zvakare kuwanazve chinhu chakajairika kune avo vakabudirira kurasikirwa uremu kuburikidza nekudya nekurovedza muviri wega. Ne semaglaride, vanhu vamwe vanhu vanogona kuwana yavo yekurasikirwa yekurasikirwa zvinangwa uye chengetedza kufambira mberi kwavo, zvichitungamira kuhutano hwakazara uye hupenyu hwehupenyu.
Uyezve, semaglutudide majekiseni anopa iyo yakakodzera uye iri nyore-kushandisa sarudzo yekugadzira uremu. Yakatumirwa kamwe chete pasvondo kuburikidza neyakajeka subcutaneous jekiseni, Semaglutudi inobvisa kudiwa kwekushanya kwekurapa kwekurapa kana kuomarara kurapa. Izvi nyore kuzviita sarudzo inokwezva kune vanhu vanogona kunetseka nekuomerera kune kumwe kurema kwekupindira.
Pamusoro pezvo, Semaglutudide yakaratidzwa kuve neruzivo rwakanaka rwekuchengetedza, neruzhinji rwevatori vechikamu mumiedzo yekiriniki inosangana chete mumigwagwa zvine mwero. Aya marongero, akadai sekushungurudzika uye manyoka, anowanzo shinda uye atsunga nekuenderera mberi kurapwa. Zvakawanda, zvakanakira sameglutudie majekiseni ehuremu akajeka, achipa mhinduro inobudirira uye yakakodzera kuti vanhu vatarisire kutora huremu hwavo uye kuvandudza hutano hwavo.
Semaglutide inobatsira sei kudzora kusuwa uye zvinokatyamadza
Chimwe chezvinhu zvakakosha zvinopa kufutisa ndiko kuvapo kwekugara kwezwenza uye kushuva, izvo zvinogona kukanganisa kunyange zvakanyanya kurambidza uremu kuedza kurema. Semaglutide inogadzirisa nyaya iyi nekuvanza iyo nzvimbo yekudyara-kutevedzera, ichibatsira kuderedza kunzwa kwenzara uye curb cravings.
Tsvagurudzo yakaratidza kuti jeglutudide majekiseni anogona kuderedza zvakanyanya chishuvo chekudya, kunyanya yakanyanya-calorie uye yakakwirira-mafuta chikafu. Iyi mhedzisiro inofungidzirwa kuti ichirevedzwa kuburikidza neiyo activation yeGLP-1 Receptors muuropi, iyo inoshandura modulate
Nekudzora kushuva uye kushuva, semaglutide inoita kuti vanhu vaite sarudzo dzakanaka uye kuomerera kune yakaderedzwa-calorie chikafu chikawedzera. Izvi, zvichitungamira pakurema kwakakura uremu uye kwakavandudzika metabolic hutano. Zvakare, Semaglutide's Kudya-kudzvinyirira mhedzisiro inowedzera kupfuura iyo nguva yeiyo jekiseni, ichibatsira kutanga maitiro ekudya nehutano uye maitiro kwenguva yakareba.
Kune vamwe vanhu vanonetsekana nekudya kwemanzwiro kana kuita zvekudya zvekudya zvekudya, semaglutide inogona kupa chishandiso chakakosha chekupwanya kutenderera kwekudya nekuwana shanduko isingaperi. Nekutaura nezvechisimba chebenzi
Chiratidzo chekiriniki chinotsigira kushandiswa kweiyo semaglutide yekufutisa kurapwa
Kubudirira kweguva yekufutisa kurapwa kwakadzidziswa zvakanyanya mumiedzo yekiriniki, ine humbowo hunogombedzera hunotsigira kushandiswa kwayo senzira yakachengeteka uye inoshanda yehuremu hwehuremu hwehuremu.
Mune imwe nguva yekubvunda, inozivikanwa sedanho (Semaglutide kurapwa kurapwa muvanhu nekufutisa miganho yehuremu pakuremerwa kwehuremu uye metabol. Mhedzisiro yacho yakanga ichirova: Vatori vechikamu vachigamuchira semaglutudide majekiseni akasangana zvakanyanya nehuremu hwakanyanya kuenzaniswa neavo vanogashira placebo, nekudzikisira mumuviri misa index (BMI) uye chiuno kutenderera.
Uyezve, kurapwa kwemagarari kwakabatana nekuvandudzwa muzvinhu zvakasiyana-siyana zvine chekuita nekwavo, kusanganisira hypertension, Dyslolidmia, uye Type 2 chirwere cheshuga. Izvi zvakawanikwa zvakaratidza kusanganiswa kweganho rakakura mumatanho makuru ekutonga kwekufutisa, sekuti izvo zvakabudiswa neAmerican kushamwaridzana uye kubatana kweEuropean kwekudzidza kwechirwere cheshuga.
Vanhu vamwe vachitarisisa mhinduro dzinobudirira uye dzakasarudzika dzekurema, masajasi jekiseni rakatsauka kuti rirege kurapwa, nekupa chishandiso chakasimba chekuwana huremu hwekuremara kwenguva refu uye nekuvandudzwa kwehutano hwehutano.
Mhedziso
Semaglutide jekiseni yakabuda seyakaganhurana sosi yekunetseka kwevanhu vanonetsekana nekufutisa, kupa sarudzo inoshanda uye nyore nyore kwenguva refu yekurema uye kusatenderwa. Nechiratidzo chakamanikidza
Sezvo nyanzvi dzehutano uye vanhu vakafanana vanoziva kugona kweiyo semaglutude kushandura hupenyu, zvakakanganisika kuti vaenderere mberi nekutsvaga mabhenefiti ayo uye kururamisa kushandiswa kwayo mukuita kwechiremba. Nekusunga masimba ejecha rejasi, tinogona kupa simba vanhu kuti vatore huremu hwavo, tichivandudza hutano hwavo hwese, uye kuwana shanduko isingaperi muhondo yekurwa nekufumwisa.
