PLLA Deraml Filler
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Product Name | PLLA Deraml Filler |
Type | PllaHAfill® Lidocaine 1mL |
Needle | 2 x 27G |
Ingredient | 17mg/mL Sodium Hyaluronate 18% PLLA-b-PEG microsphere 0.3% Lidocaine |
Injection Areas |
It should be used by an authorized practitioner. Do not re-sterilize or mix with other products. |
Injection Depth | Deep dermis, superficial or deep subcutaneous layer |
1mL PLLA Hyaluronic Acid Filler carries ISO 13485, CE, GMP and SGS certifications, along with a detailed Material Safety Data Sheet. These credentials confirm our strict quality management, EU regulatory compliance, and commitment to user safety at every production stage.


Our global customer gallery spans over 20+ years and shows real results from a single PllaHAfill® treatment. You can see clear facial contour improvements and lasting effects up to two years across different skin types and ages.

Pain Free 1ML PllaHAfiller Injection: An Innovative Technological Path for Facial Rejuvenation
PllaHAfill® is an advanced dermal filler specifically designed to correct moderate to severe facial wrinkles and improve facial contours. It can be used for deep, superficial or deep subcutaneous injection in the dermis, and is suitable for areas such as the forehead, temples, eyebrow arches, nasal bridge, nasal columella, nasal floor, cheeks, jawline and chin. It can effectively fill and improve facial aging problems such as nasolabial folds and wrinkles.
The PllaHAfill® adopts a dual-effect mechanism of immediate filling and long-lasting regeneration, providing a phased improvement solution for facial rejuvenation. Sodium hyaluronate, with precise concentration ratios, can immediately replenish tissue volume after injection and significantly improve wrinkles. PLA-b-PEG microspheres can continuously release biological signals, activate the activity of fibroblasts, promote collagen synthesis, reshape the skin structure at the extracellular matrix level, and achieve long-term effects.
PLLA is a medical-grade polymer that has passed international biosafety certification and can gradually degrade into carbon dioxide and water in the body. After injection, PLLA forms a three-dimensional microscaffold structure, activates the signaling pathways within fibroblasts, and promotes collagen production in a targeted manner. Clinical data shows that after a single injection, the improvement in skin firmness can last for up to 18 months.
HA is made from non-animal-derived raw materials and processed through cross-linking technology to form a highly viscoelastic gel texture. This texture enables it to precisely replenish the volume during injection while providing stable support. The HA component can not only immediately improve the sunken facial contours, but also significantly increase the skin's moisture content in a short period of time, reshaping the facial aesthetic structure.
PllaHAfill® has shown significant therapeutic value in multiple areas of the face. In the frontotemporal region, it can restore the golden ratio of the upper one-third of the face. In the nasolabial area, it can precisely support and maintain a natural transition under dynamic expressions. In the mandibular contour, it can reshape the V-shaped contour through the synergistic effect of PLLA-induced collagen tightening and immediate shaping by HA.
This product is suitable for people with mild to moderate aging, those who need refined facial contours, people with sensitive constitutions, and users who expect long-term treatment. Its non-animal-derived raw materials minimize the risk of allergies. Meanwhile, the effect of a single treatment can last for 12 to 24 months, reducing the frequency of treatment.
To ensure the continuity and safety of the treatment effect, it is recommended to avoid pressure on the injection area within 24 hours after the operation and use cold compresses to relieve swelling. It is recommended to use sunscreen and avoid exposure to high-temperature environments within 1 to 3 months after the operation. In addition, it is recommended to establish a standardized follow-up system and conduct regular skin tests and clinical evaluations.
- Long-lasting Stability: The ingredients of PllaHAfill® make its effect far exceed that of traditional hyaluronic acid fillers, maintaining facial rejuvenation for a long time and eliminating the need for frequent treatments for those seeking beauty.
- Natural Shaping Effect: By gradually stimulating collagen production, PllaHAfill® can achieve natural skin improvement and shaping effects, avoiding the unnatural feeling caused by excessive filling, making the facial contour softer and more natural.
- High Cost Performance: A single injection can maintain the effect for up to 1 to 2 years, reducing the number of repeated treatments and costs, providing a cost-effective facial rejuvenation solution for those seeking beauty.
- Remarkable Anti-aging Effect: PllaHAfill® can effectively improve skin aging issues such as wrinkles, sagging, and depressions, enhancing skin firmness and elasticity from the root, and restoring the radiance of the face.
Guangzhou AOMA Biotechnology Co., LTD. : Customized sodium hyaluronate gel solutions to facilitate brand outstanding growth
With a legacy of pioneering excellence in sodium hyaluronate gel manufacturing, Guangzhou AOMA Biological Technology Co., Ltd. stands out as a top-tier GMP pharmaceutical production facility globally. Leveraging over 21 years of experience and a diverse portfolio of proven formulations, we have partnered with 580 esteemed brands to deliver customized solutions, achieving an exceptional 99.5% customer satisfaction rating.
Tailoring Your Brand Identity
Collaborate with us to design a creative logo that embodies your brand's essence and ensures recognition across all product touchpoints, from ampoules to vials, boxes, and labels.
Crafting Unique Formulations
Empower your customers with tailored products using our high-quality ingredients, including Type III Collagen, Lido-caine, Polydeoxyribonucleotide (PDRN), Poly-L-Lactic Acid (PLLA), and Semaglutide (subject to regulations), offering a range of benefits from skin health to comfort during application and rejuvenation.
Meeting Your Production Demands
Adapt to your production requirements with a range of ampoule sizes, BD syringe volumes (1ml, 2ml, 10ml & 20ml), and vial capacities, ensuring your product line is optimized to meet market demands effectively.
Engaging Packaging Design Custom Packaging Solutions:
Elevate your brand's visual identity with packaging that not only protects but captivates.
Collaborate with our experts to create unique packaging designs using sustainable materials aligned with your brand's values, captivating customers with aesthetics that inform and entice.
How does this product achieve multi dimensional aesthetic enhancement?
It stimulates deep layer collagen to fill nasolabial folds, restoring firmness and elasticity for up to two years.
How long do I see the filler effect after using 1mL PLLA Hyaluronic Acid Filler?
Immediate firming occurs post injection, with progressive nasolabial improvement peaking at three to six months.
1mL PLLA Hyaluronic Acid Filler is suitable for what groups?
Ideal for those seeking nasolabial fold correction, especially if unsatisfied with traditional fillers or concerned about side effects.
Which is better 1mL PLLA Hyaluronic Acid Filler or Hyaluronic Acid filler?
HA offers instant results; PLLA provides lasting collagen stimulation and volume restoration over time.
Do you offer stable long-term supply for growing brands and distributors?
Yes, we have robust production capacity for consistent long-term supply.
![]() Logo Design | Logo Design on Ampoules | Logo Design on Product Box |
Logo Design on Dermal Filler Packaging | Logo Design on Vials | Logo Design on Dermal Filler Label |
![]() +III Collagen | ![]() +Lidocaine | +PDRN |
+PLLA | +Semaglutide | +Semaglutide |
![]() Ampoules | Ampoules | BD 1ml 2ml 10ml 20ml Syringes |
Vials |
Packaging Customization | ![]() Packaging Customization | Packaging Customization |
Packaging Customization | Packaging Customization | Packaging Customization |
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