Switching from Saxenda (liraglutide, daily) to Wegovy (semaglutide, weekly) is common for patients seeking greater weight loss or fewer injections. Based on the official US labels and published guidance, this guide explains why patients switch, compares the dosing schedules, and outlines the transition step by step: no washout is needed, Wegovy can usually start the day after the last Saxenda dose, the starting dose is typically 0.25 mg (0.5 mg considered off-label for some patients stable on 3 mg), and escalation occurs every 4 weeks. It also covers expected GI side effects, STEP 8 trial results, common mistakes and what the GLP-1 trend means for aesthetic clinics and distributors.
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