You want something that helps your skin stay smooth and young. PLLA filler, like AOMA's, helps your body make more collagen. It does not work like regular fillers. PLLA makes your skin react gently. This leads to slow and lasting changes. It helps fight aging and keeps you looking natural. The table below shows how PLLA filler is different from hyaluronic acid fillers:
Filler Type | How It Works | Collagen Made | How Long It Lasts |
PLLA | Starts a small skin reaction | Slow increase | Lasts a long time |
HA | Adds fullness right away | Fast increase | Does not last as long |
Key Takeaways
PLLA filler helps your skin make more collagen. This makes your skin look younger and smoother as time goes on.
You will see changes slowly. Most people notice better skin about three months after getting PLLA filler.
PLLA is safe for your body. It breaks down naturally, so it is a good choice if you want better skin without surgery.
You might need more than one session to get the best results. Collagen keeps growing for up to two years after treatment.
Using PLLA with other treatments can make your skin even better. Your skin can become firmer and healthier this way.
What Is PLLA Filler?
PLLA Composition
You might ask why PLLA filler is different. This filler uses poly-l-lactic acid as its main part. Poly-l-lactic acid comes from things like cornstarch and sugar cane. It is safe for your body and will break down slowly. Doctors use this material in many medical tools because it does not hurt you.
Here is a table that lists the main parts and what they do for safety:
Component | Role in Biocompatibility |
Poly-L-lactic acid (PLLA) | Safe, biodegradable, and used in medical applications |
Mannitol | Keeps the filler stable and safe |
Sodium carboxymethylcellulose | Makes the filler smooth and easy to inject |
PLLA microparticles | Sized to avoid unwanted reactions and allow easy injection |
Chemical attributes (pH, charge) | Help the filler work well with your body |
Hydrophobic surface | Affects how cells and proteins interact with the filler |
PLLA is strong and helps your skin heal. It can help your skin grow new tissue. Some research says PLLA may even help stop infection. You can trust PLLA because it follows strict safety rules in the US and Europe. Groups check the data to make sure it works and is safe.
Bio-Stimulatory Properties
PLLA does more than just fill space under your skin. It works as a bio-stimulator. When you get PLLA filler, tiny pieces start a gentle reaction in your body. This tells your cells to make more collagen. Collagen is a protein that keeps your skin firm and smooth.
Doctors use PLLA in many places. You can get this treatment for your face, hands, or chest. Studies show over 80% of people who get PLLA in their hands are happy with it. The results can last up to three years for some people. You may notice thicker and more stretchy skin after treatment. PLLA works best for adults between 37 and 72 years old. Most people who get it are about 50 years old.
PLLA filler is special because it helps your body renew itself. You get results that look natural and last a long time.
PLLA Collagen Stimulation Mechanism
How PLLA Particles Work
When you get a PLLA filler, small PLLA particles go into your skin. Your body notices these new particles right away. This makes your body start a gentle reaction. Your immune system sends special cells to help. These cells are called neutrophils and macrophages. They clean up and help your skin get ready to heal.
PLLA particles break down slowly over time. As they do, they let out lactate monomers. This makes your skin a little more acidic. The change in your skin helps turn on growth factors like TGF-β. These growth factors tell your skin to make more collagen. This does not happen fast. It takes weeks for your body to start making new collagen.
Here is a table that shows how PLLA helps your skin make more collagen:
Mechanism | Description |
Lactate Release | PLLA breaks down and lets out lactate, which changes the skin's pH. |
TGF-β Activation | The acid in your skin turns on TGF-β, which helps fibroblasts grow. |
Collagen Synthesis | Fibroblasts make new collagen and build up the skin's support. |
Signaling Pathways | p38, Akt, and JNK help make more collagen and move cells. |
Fibroblast Activation
Fibroblasts are needed to make more collagen in your skin. After PLLA goes in, your immune system sends monocytes. These monocytes turn into macrophages and giant cells. These cells bring fibroblasts to the spot. Fibroblasts act like builders. They start making new collagen fibers.
You will not see changes right away. Fibroblasts start working a few weeks after your PLLA treatment. You will notice your skin changing in two to three months. Your skin feels firmer and looks smoother as collagen grows. This process keeps going for months and gives you results that last.
Tip: You can help your skin make more collagen by listening to your doctor. Most people need more than one treatment. Doctors say you should wait at least 30 days between sessions. This gives your skin time to react and make more collagen.
Neocollagenesis Process
Neocollagenesis means your body makes new collagen. After you get PLLA filler, your skin goes through different steps. First, your immune system reacts to the PLLA particles. Neutrophils and macrophages come in the first ten days. They help your skin start to heal. Next, your skin makes new tissue and blood vessels. This step lasts for months.
The reaction in your skin slows down after six months. Your skin keeps making collagen. Your skin gets thicker and stronger for up to two years. PLLA acts like a scaffold for your skin. It gives support while your body makes new collagen. This helps your skin stay firm and stretchy.
You get more type III collagen after PLLA treatment. The amount of type I compared to type III collagen goes down. Collagen fibers get denser in all skin types. This means your skin looks healthier and feels younger.
PLLA filler causes a gentle reaction. This helps your skin fight aging and stay strong.
Collagen goes up over time as PLLA breaks down.
Studies show more collagen in the skin from one week to twelve weeks after treatment.
PLLA's scaffold effect helps your skin for a long time. The particles break down slowly. Your body takes them in naturally. You do not need surgery to take anything out. PLLA helps your skin heal and make more collagen for lasting results.
PLLA Filler Results and Longevity
Timeline of Improvements
You will notice that PLLA filler does not give instant changes. The process works slowly. After your first treatment, your skin starts to build new collagen. Most people see early improvements in about three months. At this point, over 80% of patients report that their skin looks better and feels firmer. You may see your face or hands look smoother and more youthful. The changes keep building as your body continues collagen production.
Note: You may need more than one treatment to reach your best results. Your doctor will help you plan the right schedule.
Natural-Looking Enhancements
PLLA gives you natural-looking results. The changes happen slowly, so your friends and family will notice you look refreshed, not different. Your skin gets firmer and lines fade, but you still look like yourself. Many patients say they feel happier and more confident after treatment. They also report better quality of life and higher self-esteem.
Here is a table that shows how patients feel about PLLA compared to other fillers:
Filler Type | Patient Satisfaction | Wrinkle Assessment Scale Improvement | Age Group Impact |
PLLA | High | Significant improvement | Superior in younger patients |
Hyaluronic Acid | Moderate | Noninferior results | N/A |
You will need fewer touch-ups with PLLA than with other fillers. This means less time in the clinic and more time enjoying your long-lasting results.
Duration of Effects
PLLA stands out for its long-lasting results. The effects can last from one to three years. Some people see results for over 36 months. This happens because PLLA breaks down slowly and keeps stimulating collagen production. You get firm, youthful skin for a long time. You can use this non-surgical treatment on your face, hands, chest, and even for breast enhancement. PLLA gives you a versatile and non-surgical way to fight aging and keep your skin looking its best.
PLLA vs. Sculptra and Other Collagen Stimulators
Key Differences
You might wonder how PLLA collagen stimulators are different from sculptra and other choices. Both PLLA and sculptra use poly-l-lactic acid to help your skin make more collagen. Sculptra is a collagen stimulator that helps your skin build collagen slowly. The PLLA microparticles in sculptra break down over time. This leaves new collagen that lasts. You cannot dissolve sculptra like hyaluronic acid fillers. So, you need to think carefully before picking this treatment.
There are also differences in the size and shape of the particles. Some PLLA collagen stimulators, like PLLA-LASYNPRO™, have small, smooth, round particles that mix well. Others, such as PLLA-SCA, have bigger, uneven particles that settle fast and can make foam. The size of the particles is important. Smaller, even particles help your body react gently and fix tissue. Bigger particles do not get eaten by cells and go through needles easily.
Here is a table that shows how PLLA filler compares to other collagen stimulators:
Filler Type | Longevity | Fibroblast Activity | Collagen Synthesis |
PLLA | Longer-lasting | Unfavorable effects | Stimulates collagen synthesis |
HA | Shorter-lasting | Favorable effects | Promotes type I collagen synthesis |
Benefits of PLLA Collagen Stimulators
You get many good things when you pick PLLA collagen stimulators. These fillers last longer than most others. You see changes that happen slowly and look natural. The slow process helps you avoid looking very different all at once. You can enjoy firmer and smoother skin for a long time.
PLLA collagen stimulators work in many places. You can use them on your face, hands, chest, and even for breast enhancement. This means you can treat many signs of aging with one kind of filler. You also need fewer touch-ups, so you save time and effort.
Tip: PLLA collagen stimulators give you a gentle lift and help your skin renew itself. You get results that last and look natural.
Combination Treatments
You can use PLLA collagen stimulators with other treatments for better results. Many doctors mix these stimulators with energy devices like lasers or ultrasound. This helps your skin make more collagen and look smoother. You can treat many signs of aging at the same time.
Here are some benefits of using PLLA collagen stimulators with other treatments:
Better results for smoother, firmer skin
More collagen for younger-looking skin
Shorter recovery time after treatment
Safe and works for many skin types
Results last a long time and keep you looking good
You may see even more changes when you use PLLA collagen stimulators with treatments like HIFU. This helps add volume, tighten skin, and make new collagen. Studies show this mix is safe and does not cause problems, even in areas that move a lot.
You can trust PLLA collagen stimulators to give you flexible, long-lasting results. You get the chance to refresh your look and keep your skin healthy.
Conclusion
You can pick PLLA filler like AOMA's to help your skin. It brings back volume and makes your skin look better. PLLA helps your body make more collagen. This gives you results that last and look natural. You do not need surgery for this treatment. You can use PLLA on your face or body. Many people use it for different beauty treatments. Studies say PLLA is safe and works well. Most patients do not have problems after treatment. You can mix PLLA with other treatments. This can make your skin even healthier and younger.
FAQ
1. How long does it take to see results from PLLA filler?
You usually notice changes after about three months. Your body needs time to build new collagen. The results appear slowly and look natural.
2. Is PLLA filler safe for all skin types?
Doctors use PLLA filler on many skin types. Most people do not have problems. You should talk to your provider before treatment to make sure it is right for you.
3. Can I combine PLLA filler with other treatments?
You can combine PLLA filler with treatments like lasers or microneedling. This helps you get better results and smoother skin. Your doctor will guide you on the best plan.
4. How many sessions will I need?
Most people need two to four sessions for the best results. Your provider will help you decide how many treatments fit your needs.
5. Does PLLA filler require downtime?
You can return to your daily activities right after treatment. Some people notice mild swelling or redness, but these effects go away quickly.
